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Abasic oligodeoxyribonucleoside phosphorothioates: synthesis and evaluation as anti-HIV-1 agents.

机译：脱碱基的寡脱氧核糖核苷硫代磷酸酯：合成和评估作为抗HIV-1剂。

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摘要

The syntheses and anti-HIV-1 evaluations of two, abasic oligodeoxyribonucleotide phosphorothioate analogs, d[Cps(Eps)26C] and d[Cps(Vps)26C] (where E and V derive from 1,2-dideoxy-D-ribofuranose and (+/-)-butane 1, 3-diol, respectively), are described.

机译：两种低聚脱氧核糖核苷酸硫代磷酸酯类似物d [Cps（Eps）26C]和d [Cps（Vps）26C]（其中E和V衍生自1,2-二脱氧-D-核呋喃呋喃糖）的合成及抗HIV-1评估（分别为（+/-）-丁烷1，3-二醇）。

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作者
Iyer, R P; Uznanski, B; Boal, J; Storm, C; Egan, W; Matsukura, M; Broder, S; Zon, G; Wilk, A; Koziolkiewicz, M;
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年度 1990
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正文语种 en
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专利

1. Abasic oligodeoxyribonucleoside phosphorothioates: synthesis and evaluation as anti-HIV-1 agents [J] . Andrzej Wilk, Bogdan Uznanski, Christy Storm, Nucleic acids research . 1990 ,第10期

机译：脱硫寡脱氧核糖核苷硫代磷酸酯：合成和评估作为抗HIV-1剂
2. Synthesis of oligodeoxyribonucleoside phosphorothioates using Lawesson's reagent for the sulfur transfer step. [J] . Ju J, McKenna CE Bioorganic and Medicinal Chemistry Letters . 2002 ,第12期

机译：使用Lawesson试剂进行硫转移步骤合成寡脱氧核糖核苷硫代磷酸酯。
3. Synthesis and evaluation of 2-(2,6-dihalophenyl)-3-pyrimidinyl-1,3-thiazolidin-4-one analogues as anti-HIV-1 agents. [J] . Rawal RK, Tripathi R, Katti SB, Bioorganic and medicinal chemistry . 2007 ,第9期

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4. Synthesis and toxicological activity of 5-nitroindazole sulfonamides derivatives as potential antimicrobial agents. Optimization of the synthesis [C] . Corina Cheptea, Andreea-Celia Benchea, Marius Găină, 2017 E-Health and Bioengineering Conference . 2017

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5. Design, synthesis, and biological evaluation of betulinic acid derivatives as potent anti-HIV-1 agents. [D] . Qian, Keduo. 2008

机译：作为有效的抗HIV-1药物的桦木酸衍生物的设计，合成和生物学评估。
6. Abasic oligodeoxyribonucleoside phosphorothioates: synthesis and evaluation as anti-HIV-1 agents. [O] . R P Iyer, B Uznanski, J Boal, 1990

机译：脱碱基的寡脱氧核糖核苷硫代磷酸酯：合成和评估作为抗HIV-1剂。
7. Synthesis and evaluation of selected benzimidazole derivatives as potential antimicrobial agents. An investigation into the synthesis of substituted benzimidazoles and their evaluation in vitro for antimicrobial activity. [O] . Alasmary Fatmah Ali Saeed 2013

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8. Synthesis of Some 4-Quinolones and Related Structures for Evaluation as Potential Anti-Malarial Agents. [R] . casey, adria c. 1973

机译：一些4-喹诺酮和相关结构的合成用于评价潜在的抗疟疾药物。

Abasic oligodeoxyribonucleoside phosphorothioates: synthesis and evaluation as anti-HIV-1 agents.

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